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RESEARCH HIGHLIGHTS
By Lars W. Andersen, Professor, Aarhus University Hospital, Denmark
Use of Automated External Defibrillators in Private Homes
Bystander interventions, including cardiopulmonary resuscitation (CPR) and the use of automated 
external defibrillators (AEDs), are increasingly common and recognized as critical components of the 
chain of survival. The use of AEDs has primarily been studied in public locations, where cardiac arrests 
are more visible and AED access is more common. A previous study using data from the Cardiac Arrest 
Registry to Enhance Survival (CARES) found that application of an AED is 
associated with improved outcomes in patients with out-of-hospital cardiac 
arrest presenting with a shockable rhythm (i.e., ventricular fibrillation or 
pulseless ventricular tachycardia) in a public location. A subsequent cost-
effectiveness analysis demonstrated that AEDs are cost-effective in many 
public settings with a relatively high incidence of cardiac arrest. 
In contrast, there has been less focus on cardiac arrests occurring in private 
homes, which account for approximately 70–80% of all out-of-hospital 
cardiac arrests. Patients experiencing cardiac arrest in the home setting 
generally have worse outcomes, are less likely to present with a shockable 
rhythm, are less likely to receive bystander CPR, and often experience 
longer emergency medical services (EMS) response times compared 
with patients in public locations. Additionally, the incidence of cardiac 
arrest within any individual home is relatively low, making targeted AED 
placement challenging. Although the purchase of AEDs for private homes 
is increasingly discussed in the media and considered by some individuals, 
AEDs remain relatively expensive, and their effectiveness and cost-
effectiveness in the home setting remain uncertain.
This study consisted of two complementary analyses. In the first, we used 
data from 582,536 patients in the CARES registry to evaluate whether AED 
use was associated with improved outcomes for patients experiencing 
cardiac arrest in a private home. In the second, we used these results 
alongside existing literature to assess whether the purchase of AEDs for 
private homes could be considered cost-effective.

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