53 Figure 16. Unadjusted pre-hospital and in-hospital OHCA patient outcomes. Survival Outcomes Based on local EMS agency protocols, 43.4% of patients were pronounced on scene after resuscitative efforts were terminated in the pre-hospital setting (Figure 16). The success of resuscitation efforts in the field is often measured by a patient’s return of spontaneous circulation (ROSC). In 2025, sustained ROSC (defined as 20 consecutive minutes of ROSC, or its presence at transfer of care to a receiving hospital) was achieved by 22.8% of CARES patients. The rate of survival to hospital admission was 25.3% (ED outcome missing for 241 cases; 0.2%), and the rate of survival to hospital discharge was 10.5% (hospital outcome missing for 283 cases; 0.2%). Among patients discharged alive, the majority had a neurologically favorable outcome, indicated by a Cerebral Performance Category (CPC) score of 1 or 2 (Table 3). Patient Outcomes Table 3. Cerebral Performance Category (CPC) Scores CPC Score Description CPC 1 Good Cerebral Performance Conscious, alert, able to work and lead a normal life. CPC 2 Moderate Cerebral Disability Conscious and able to function independently (dress, travel, prepare food), but may have hemiplegia, seizures, or permanent memory or mental changes. CPC 3 Severe Cerebral Disability Conscious, dependent on others for daily support because of impaired brain function (in an institution or at home with exceptional family effort). CPC 4 Coma, Vegetative State Not conscious. Unaware of surroundings, no cognition. No verbal or psychological interactions with environment. CPC 5 Death
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